Custom Synthesis

Analytica Chemie Inc has state-of-the-art synthetic laboratories that are ISO 9001:2015 certified. Our synthetic facility includes R&D labs and kilo labs, both measuring about 5000 sqft. Our labs are equipped to handle all kinds of reactions with latest technology such as Microwave Reactors, Flow Chemistry, Photochemical Reactors, Peptide Synthesizers etc. We also have special expertise and infrastructure to handle sensitive / hazardous reagents.

We have a team of Synthetic Organic Chemists with in-depth knowledge and experience in complex organic syntheses including prostaglandins, alkaloids, steroids, terpenoids, antibiotic products, heterocyclic compounds, carbohydrates and peptides etc. Our scientists are well trained to design and synthesize difficult-to-make, complex organic compounds using cutting edge technologies and methods with multi steps, ranging from milligrams to kilograms. We also have a dedicated planning team consisting of well experienced Synthetic Organic Chemists who have extensive experience in cost effective synthesis route scouting, process development and optimization through DoE and QbD.

We offer services on synthesis of all kinds of bioactive molecules such as alkaloids, terpenoids, steroids, heterocyclic compound, carbohydrate based compounds, antibiotics etc.

What we offer:

• Synthesis of impurity standards and reference standards
• Synthesis of metabolites and degradation impurities
• Synthesis of genotoxic impurities
• Synthesis of APIs and advanced intermediates
• Stable isotope labelled compounds
• Customized Synthesis of NCEs
• Development of new synthetic routes
• Process development
• Peptide synthesis

Indicative list of other synthesis capabilities includes (but not limited to)

• Grignard Reactions
• Friedel-craft reactions
• LiAlH4, NaCNBH3 based reactions
• n-Butyl lithium and LDA reactions
• NaH / KH, Sodium/Potassium alkoxide, Sodamide reactions
• Reaction containing catalyst like Pd/C, PtO2, Raney-Nickel
• Halogenation reactions (chlorination, bromination and iodination)
• General protection and deprotection of functional groups
• High pressure reactions
• Reaction containing lacrimatic, corrosive, moisture sensitive, hazardous reagents
• Suzuki, Heck, Stile reactions
• Asymmetric synthesis & resolution of enantiomers
• Deuterium Chemistry
• Organometallic chemistry
• Microwave assisted organic synthesis
• Metal mediated organic transformations
• Photochemical reactions
• Enzymatic reactions
• Peptide synthesis
• Enzymatic synthesis
• Chiral synthesis